Advanced Fuels Infrastructure Research and Development Act - Instructs the Assistant Administrator of the Office of Research and Development of the Environmental Protection Agency (EPA) to implement a program of research and development of materials to be added to biofuels to make them more compatible with existing infrastructure used to store and deliver petroleum-based fuels to the point of final sale.
Cites problem areas to be addressed, including microbial contamination.
Directs the Assistant Administrator to: (1) implement a research, development, demonstration program on portable, low-cost, and accurate methods and technologies for testing sulfur content in fuel, including Ultra Low Sulfur Diesel and Low Sulfur Diesel; and (2) begin demonstrations of such technologies within a year after enactment of this Act.
Directs the National Institute of Standards and Technology to develop a physical properties database and standard reference materials for biofuels.
Authorizes appropriations to EPA to implement this Act.