Consumer Protection in Airline Ticket Validity Act of 2010 - Makes it an unfair or deceptive practice for any air carrier, foreign air carrier, or ticket agent to: (1) sell an airline ticket that expires before the last day of the three-year period beginning upon the ticket's issuance; or (2) impose unreasonable restrictions, penalties, or fees on requests to reschedule an air passenger's itinerary that occur before the ticket expires.