This bill establishes a coordinated effort to further improve Onondaga Lake in New York by creating the Onondaga Lake Watershed Council and requiring the EPA Administrator to develop and implement an Adaptive Management Plan for the lake's restoration. The council will include representatives from federal and state agencies, local governments, the Onondaga Nation, and will be advised by a newly created Onondaga Lake Scientific Center composed of universities and environmental institutes. The plan will set measurable restoration goals, recommend management strategies, and establish a comprehensive scientific and engineering program to evaluate whether these strategies are working. The bill authorizes $10 million per year in federal grants to implement the plan's recommendations, with grants going to New York State, Syracuse, Onondaga County, and the Onondaga Environmental Institute, though these grantees must provide a 35 percent local match for the federal funds. The legislation emphasizes the importance of ongoing public participation and coordination with existing environmental laws and agreements governing the lake.