The Guam-Federal Consultation Act establishes a formal process for regular discussions between Guam officials and the U.S. federal government on matters affecting their relationship. Under this bill, the President and Guam's Governor must consult regularly, and designated representatives from both governments must meet at least every five years to discuss issues raised by either side, with the results submitted to Congress within 180 days. Additionally, the bill requires special representatives to meet at least one year before any major federal financial assistance to Guam expires, so they can make recommendations about future multi-year funding. The bill amends Guam's Organic Act and defines who can serve as representatives on both sides, including Guam's delegate to Congress. No specific funding amounts are allocated in the legislation, as it primarily establishes a consultation requirement rather than appropriating money.