The PUPPS Act (Prohibiting Unethical Procedures on Pets in Science Act) would ban the breeding, commercial distribution, and use of dogs specifically raised for scientific research purposes. The law would apply to research facilities, dealers, and other entities involved in acquiring or using dogs bred for laboratory work, making these activities illegal under the Animal Welfare Act. Violators would face civil penalties of up to $10,000 per dog for first-time violations and $40,000 per dog for repeated violations, with a maximum aggregate penalty of $500,000 per investigation. Dogs already in captivity for research purposes as of the bill's enactment could not be euthanized and must instead be offered for adoption to individuals or animal rescue organizations. The Department of Agriculture would have 180 days after the bill becomes law to issue regulations implementing these changes, with the prohibition taking effect 180 days after enactment.