This bill designates biotechnology and biomanufacturing infrastructure as critical infrastructure that should be protected by the Cybersecurity and Infrastructure Security Agency within the Department of Homeland Security. Currently, many biotech facilities lack formal designation as critical infrastructure, leaving them without coordinated federal cybersecurity and physical security protections. The bill requires the agency to develop a comprehensive work plan within 45 days of enactment that identifies stakeholders, creates outreach strategies, and ensures biotech companies are represented in relevant security councils and coordinating bodies. The bill also mandates an implementation report within one year and a final assessment within two years to determine whether any biotechnology areas remain inadequately protected. No specific funding amounts are included in the legislation, though it directs existing federal resources to be applied to this new protective mission.