H.R. 3677 would convert President Biden's Executive Order 14292 into permanent law by codifying its requirements for improving safety and security in biological research. The bill affects research institutions, universities, and laboratories that conduct biological work, as well as federal agencies overseeing such research. Rather than relying on an executive order that could be reversed by a future president, this legislation would lock in the safety and security standards into statute, making them binding unless Congress acts to change them. The bill provides no new funding or specific implementation timelines, instead simply giving legal permanence to the requirements established in the original executive order signed on May 5, 2025. The measure was introduced on June 3, 2025, and referred to the House Committees on Energy and Commerce and Science, Space, and Technology for review.