This bill establishes the Endless Mountains National Heritage Area in Pennsylvania as an official part of the National Heritage Area System, covering Bradford, Sullivan, Susquehanna, and Wyoming counties, along with any additional areas identified in a related feasibility study. It designates the Endless Mountains Heritage Region, Inc. as the local organization responsible for coordinating the area's activities and management. This nonprofit group must submit a management plan to the Secretary of the Interior for approval within three years of the bill becoming law. The legislation primarily affects residents, local governments, and organizations in these four Pennsylvania counties by making the region eligible for federal recognition and support tied to heritage preservation and tourism efforts. Federal assistance for the heritage area will expire 15 years after the bill's enactment, setting a clear timeline for the program's federal involvement.