The Biosecurity Smuggling Deterrence Act of 2026 imposes mandatory minimum prison sentences for crimes related to illegally bringing biological agents into the United States. Specifically, anyone convicted of conspiring to smuggle biological agents or actually smuggling them faces a mandatory minimum of 20 years in prison, while those who make false statements to federal authorities in connection with such smuggling face a mandatory minimum of 5 years. The bill applies to dangerous biological materials as defined under federal law and affects anyone involved in these smuggling operations, from planners to those providing false information to government agents. The law takes effect immediately upon enactment and applies to all offenses committed after the bill becomes law. This legislation aims to deter attempts to illegally import dangerous biological materials that could pose public health or security threats.