This bill strengthens the federal government's ability to detect and prosecute health care fraud by significantly increasing funding for anti-fraud programs through fiscal year 2029 and beyond. The legislation provides increased funding for the Department of Health and Human Services, Department of Justice, FBI, and Medicare Integrity Program, with amounts ranging from $490 million to $1.48 billion annually depending on the agency and year, with automatic adjustments for inflation after 2029. The bill expands the Office of the Inspector General's investigative authority to cover additional health insurance programs beyond Medicare and Medicaid, and requires annual reports to Congress on fraud prevention activities with specific notice requirements if reports are delayed. Additionally, the bill directs the Government Accountability Office to study the effectiveness of these fraud prevention programs and report findings to Congress within 16 months of enactment, and extends fraud detection efforts to include the State Children's Health Insurance Program beginning in 2027.