The Americans First Immigration Act proposes comprehensive changes to U.S. immigration law designed to prioritize American workers and restrict family-based immigration. The bill establishes strict employer requirements for hiring foreign workers, including good-faith recruitment of U.S. workers, comparable wage offers, and a 90-day protection against layoffs, with penalties ranging from $5,000 to $50,000 for violations and up to six months in prison for willful noncompliance. It eliminates the diversity visa lottery and replaces it with a capped religious workers program, eliminates parents as immediate relatives in family immigration, and creates a new points-based employment visa system capped at 192,000 annually based on salary, education, English proficiency, military service, and age. The bill also requires all immigrants to pledge loyalty to the U.S. Constitution and renounce participation in serious crimes and human rights violations, creates a two-year conditional permanent resident status for employment-based immigrants with strict work and benefit requirements, and mandates that foreign students pay at least out-of-state tuition rates at colleges and universities.