This bill designates biotechnology and biomanufacturing infrastructure as critical infrastructure that requires protection by the federal government's Cybersecurity and Infrastructure Security Agency. The legislation amends the Homeland Security Act of 2002 to ensure that biotech facilities and biomanufacturing operations receive the same security oversight and coordination that other critical infrastructure sectors receive, and establishes a framework for the agency to work with industry groups, information sharing organizations, and sector coordinators to protect these facilities. The bill requires the Cybersecurity and Infrastructure Security Agency director to submit a work plan within 45 days of enactment that identifies biotech stakeholders, creates an outreach strategy, and ensures these industries are represented in relevant coordinating councils, with updated strategic protection plans by September 30, 2027. The director must also report back within one year on how the work plan is being implemented and within two years on whether any critical biotechnology areas remain unprotected. No specific funding amounts are mentioned in the legislation.