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Institute for Systems Biology

Public charityFed auditsIRS 990
DBA: % GARY C STREICHER
Other · SEATTLE, WA · EIN 91-2003593

Money In (latest fiscal year)

990 · FY ending 2024-12-31
Very large (approx.)
Donor contributions
$37.9M
Investment income
$3.3M
Program-service revenue
$822K
→
Total revenue
$42.3M

Grants Received (Top 50 by amount)

1,484 grants · $186.0M total
GrantorEINFYCash grantPurpose
PRESIDENT AND FELLOWS OF HARVARD COLLEGE0421035802017-06-30$1.0MSPONSORED RESEARCH SUB-AWARD
MAYO CLINIC GROUP RETURN3839526442022-12-31$1.0MSUPPORT CHARITABLE PURPOSE
PROVIDENCE HEALTH & SERVICES WASHINGTON5102165862022-12-31$742KOPERATIONAL SUPPORT
SEATTLE CHILDRENS HOSPITAL9105647482019-09-30$550KPEDIATRIC MEDICAL RESEARCH GRANT SUBAWARD
PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY4733553812019-12-31$548KSUPPORT RESEARCH IN FIELD OF CANCER IMMUNOTHERAPY
SAGE BIONETWORKS2644899462019-12-31$511KAssist in the development of an integrative platform: the Pan-cancer Immune Atlas (iAtlas) to host the data and results derived from the PanCancerAtlas Immune Response Working Group and to provide external investigators with the ability to reproduce results of the IRWG. Provide expertise related to the analyses of the metabolic and transcriptional regulatory network sand will work collaboratively to develop, implement, test, and benchmark all methods related to the dynamic analyses of the transcriptional regulatory and metabolic networks aimed at drug target discovery for Alzheimer's Disease. The Institute for Systems Biology will provide expertise related to the (dynamic) analyses of the metabolic and transcriptional regulatory networks and will work collaboratively to develop, implement, test, and benchmark all methods related to the dynamic analyses of the transcriptional regulatory and metabolic networks aimed at drug target discovery for the AMP-AD CC project.
PRESIDENT AND FELLOWS OF HARVARD COLLEGE0421035802018-06-30$500KSponsored Research Sub-Award
SAGE BIONETWORKS2644899462018-12-31$489KAssist in the development of an integrative platform: the Pan-cancer Immune Atlas (iAtlas) to host the data and results derived from the PanCancerAtlas Immune Response Working Group and to provide external investigators witht the ability to reproduce results of the IRWG. Provide expertise related to the analyses of the metabolic and transcriptional regulatory networksand will work collaboratively to develop, implement, test, and benchmark all methods related to the dynamic analyses of the transcriptional regulatory and metabolic networks aimed at drug target discovery for Alzheimer's Disease. The Institute for Systems Biology will provide expertise related to the (dynamic) analyses of the metabolic and transcriptional regulatory networks and will work collaboratively to develop, implement, test, and benchmark all methods related to the dynamic analyses of the transcriptional regulatory and metabolic networks aimed at drug target discovery for the AMP-AD CC project.
SEATTLE CHILDRENS HOSPITAL9105647482022-09-30$393KPEDIATRIC MEDICAL RESEARCH GRANT SUBAWARD
SAGE BIONETWORKS2644899462023-12-31$380KCRI Immune Atlas4: Platform for immune-oncology research and data sharing. Exceptional Longevity Data Management and Coordinating Center, design and perform cross-project analysis focused on harnessing systems biology-based techniques, such as multi-omic data integration, network analysis, machine learning, and statistical modeling, to investigate both aging and disease, as well as the interplay between them.
PRESIDENT AND FELLOWS OF HARVARD COLLEGE0421035802023-06-30$361KSPONSORED RESEARCH SUB-AWARD
SEATTLE CHILDRENS HOSPITAL9105647482023-09-30$350KPEDIATRIC MEDICAL RESEARCH GRANT SUBAWARD
SAGE BIONETWORKS2644899462017-12-31$349KAssist in the development of an integrative platform: the Pan-cancer Immune Atlas (iAtlas) to host the data and results derived from the PanCancerAtlas Immune Response Working Group and to provide external investigators witht the ability to reproduce results of the IRWG. Provide expertise related to the analyses of the metabolic and transcriptional regulatory networksand will work collaboratively to develop, implement, test, and benchmark all methods related to the dynamic analyses of the transcriptional regulatory and metabolic networks aimed at drug target discovery for Alzheimer's Disease.
CORNELL UNIVERSITY1505320822023-06-30$344KResearch
EVERY CURE INC9202407172024-12-31$309KISB WILL CURATE, EVALUATE, AND INTEGRATE LARGE BIOMEDICAL DATASETS INTO EVERY CURE'S KNOWLEDGE GRAPH, FOCUSING ON DATA QUALITY AND ONTOLOGY HARMONIZATION. THEY WILL PERFORM MANUAL CURATION, CROSS-VALIDATION, AND DEVELOPMENT OF PROTOCOLS TO ENSURE RELIABLE DRUG, DISEASE, AND MOLECULAR ASSOCIATIONS. THEIR WORK ENSURES THE SPOKE DATABASE AND OTHER KEY SOURCES ARE INCORPORATED INTO A ROBUST COMPUTATIONAL FRAMEWORK FOR DRUG REPURPOSING.